The role of chemotherapy and operation on lymphocytes accumulation in peripheral blood obtained from patients with oral squamous cell carcinoma

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Table 1 Correlations between the percentage of different lymphocyte subgroups and clinicopathologic characteristics in OSCC

Groups	N	CD3⁺CD4⁺	CD3⁺CD8⁺	CD3⁻CD19⁺	CD3⁻CD56⁺
Gender
Male	34	37.27 ± 8.29	27.79 ± 5.57	10.24 ± 5.08	18.75 ± 9.00
Female	9	36.56 ± 7.88	26.44 ± 4.98	10.58 ± 3.76	16.49 ± 8.66
Age
≤40	3	30.33 ± 4.04	22.33 ± 3.51	9.50 ± 2.17	24.60 ± 4.85
40–60	19	39.68 ± 6.95	29.58 ± 4.74^a	11.04 ± 5.63	18.48 ± 9.42
≥60	21	35.76 ± 8.84	26.38 ± 5.55	9.77 ± 4.29	17.19 ± 8.73
Location
Tongue	21	38.1 ± 8.09	27.33 ± 5.17	11.03 ± 5.89	19.14 ± 8.97
Floor of mouth	13	36.69 ± 8.04	27.92 ± 5.82	9.60 ± 3.35	17.06 ± 9.00
Buccal	9	35.44 ± 8.93	27.33 ± 6.02	9.66 ± 3.85	18.02 ± 9.31
Tumor size
T_1–2	17	29.06 ± 3.44^b	22.65 ± 3.10^c	1048 ± 4.52	15.82 ± 8.39
T_3–4	26	42.39 ± 5.49	30.69 ± 4.08	10.20 ± 5.06	19.89 ± 8.98
Nodal status
N₀	19	30.58 ± 5.04^d	24 ± 4.66^e	1045 ± 4.78	17.48 ± 9.34
N_1–3	24	42.29 ± 6.10	30.29 ± 4.30	10.20 ± 4.91	18.91 ± 8.65
Pathological grading
Well differentiated	21	40.75 ± 7.05	29.52 ± 5.12	10.48 ± 5.58	18.55 ± 8.19
Intermediate differentiated	14	33.14 ± 6.37	25 ± 4.99	10.03 ± 4.31	19.26 ± 10.39
Poor differentiated	8	33.75 ± 8.46	26.63 ± 5.42	10.36 ± 3.79	15.85 ± 8.47