Mastectomy (n = 1312) | Wide excision (n = 932) | P value | |
---|---|---|---|
Median age | 55 (23–94) | 51 (24–90) | <0.01 |
Menstrual status | 0.01 | ||
Pre-menopausal | 945 | 446 | |
Post-menopausal | 815 | 482 | |
Ethnicity | 0.06 | ||
Chinese | 1064 | 748 | |
Malay | 120 | 78 | |
Indians | 59 | 65 | |
Others | 69 | 41 | |
Presentation | <0.01 | ||
Screen detected | 219 | 324 | |
Symptomatic | 1067 | 582 | |
Median clinical tumour size (cm) | 3.0 (0.5–20) | 2.0 (0.5–6.0) | <0.01 |
Clinically palpable axillary nodes | <0.01 | ||
Yes | 149 | 26 | |
No | 1141 | 896 | |
Pre-operative diagnosis | <0.01 | ||
Invasive CA | 1092 | 673 | |
DCIS | 218 | 252 | |
Atypia | 2 | 7 | |
Neoadjuvant chemotherapy | <0.01 | ||
Yes | 93 | 13 | |
No | 1219 | 919 | |
Median pathological tumour size (mm) | 25 (1–210) | 16 (1–70) | <0.01 |
Tumour histology | <0.01 | ||
DCIS | 165 | 221 | |
IDC | 1029 | 655 | |
ILC | 76 | 22 | |
Medullary CA | 3 | 5 | |
Mucinous CA | 16 | 13 | |
Papillary CA | 3 | 7 | |
Others | 19 | 5 | |
Tumour grade | 0.09 | ||
1 | 169 | 128 | |
2 | 501 | 313 | |
3 | 451 | 265 | |
ER status | <0.01 | ||
Positive | 847 | 621 | |
Negative | 394 | 209 | |
PR status | 0.02 | ||
Positive | 618 | 456 | |
Negative | 621 | 373 | |
Nodal status | <0.01 | ||
Positive | 602 | 299 | |
Negative | 575 | 502 | |
Disease stage | <0.01 | ||
DCIS | 135 | 199 | |
I | 311 | 365 | |
II | 473 | 289 | |
III | 393 | 79 | |
ASA scorea | <0.01 | ||
1 | 81 | 62 | |
2 | 454 | 286 | |
3 | 87 | 28 |