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Table 2 Univariate and multivariate analysis of clinicopathological factors for pCR

From: Promoter methylation of TRIM9 as a marker for detection of circulating tumor DNA in breast cancer patients

Characteristics

Univariate analysis

Multivariate analysis

Odds ratio

95 % CI

P value

Odds ratio

95 % CI

P value

Age (≥50 vs <50)

3.13

1.29–7.66

0.0091

2.24

0.80-6.56

0.1236

T stage (T1+2 vs T3+4)

1.80

0.61–5.35

0.2743

   

Lymph node status (positive vs negative)

1.68

0.64–4.41

0.2858

   

ER (negative vs positive)

10.5

4.00–27.4

<0.0001

5.14

1.23–27.2

0.0240

PgR (negative vs positive)

5.60

1.95–16.1

0.0004

0.98

0.17–4.86

0.9823

HER2 (positive vs negative)

2.47

1.03–5.94

0.0440

1.98

0.69–5.76

0.2002

TRIM9 methylation (<8.2 vs ≥8.2 %)

10.6

2.96–37.6

<0.0001

3.96

0.97–20.1

0.0545

  1. CI confidence interval