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Table 2 Univariate and multivariate analysis of clinicopathological factors for pCR

From: Promoter methylation of TRIM9 as a marker for detection of circulating tumor DNA in breast cancer patients

Characteristics Univariate analysis Multivariate analysis
Odds ratio 95 % CI P value Odds ratio 95 % CI P value
Age (≥50 vs <50) 3.13 1.29–7.66 0.0091 2.24 0.80-6.56 0.1236
T stage (T1+2 vs T3+4) 1.80 0.61–5.35 0.2743    
Lymph node status (positive vs negative) 1.68 0.64–4.41 0.2858    
ER (negative vs positive) 10.5 4.00–27.4 <0.0001 5.14 1.23–27.2 0.0240
PgR (negative vs positive) 5.60 1.95–16.1 0.0004 0.98 0.17–4.86 0.9823
HER2 (positive vs negative) 2.47 1.03–5.94 0.0440 1.98 0.69–5.76 0.2002
TRIM9 methylation (<8.2 vs ≥8.2 %) 10.6 2.96–37.6 <0.0001 3.96 0.97–20.1 0.0545
  1. CI confidence interval