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Table 3 Time course of changes in blood glucose level and salivary α-amylase activities after the different glucose-loadings

From: Disrupted normal ingestion during glucose intake modulates glucose kinetics in humans

 

Blood glucose level (mg/dl)

AUBGC

s-AMY

Pre-loading

15 min

30 min

45 min

60 min

90 min

120 min

(mg/dl × min)

Pre-loading

Post-loading

60 min

Control

Mean ± SE

79.6 ± 3.0

128.4 ± 6.6

129.9 ± 8.9

130 ± 9.6

121.5 ± 10.6

105.9 ± 5.8

92 ± 5.1

14,335 ± 692

45.3 ± 4.3

42.9 ± 3.5

40.1 ± 2.4

Median

75

131.5

135.5

130.5

124

105

97

13,633

43

42

39

Inter-quartile range

11.8

21.0

35.0

35.3

20.5

10.5

12.8

1776

10.5

8.5

5.5

Nose clipping

Mean ± SE

79.8 ± 1.7

117.9 ± 4.7

118.2 ± 11.3

111.1 ± 12.2

107.2 ± 9.2

93.9 ± 7

80.1 ± 3.8

12,832 ± 745

42.3 ± 1.8

48.1 ± 2.2

42.1# ± 0.9

Median

78

122

128.5

96

106

93

80

12,607

42

47

41

Inter-quartile range

6.3

13.3

50.0

56.3

39.8

26.3

13.0

2664

3.5

6.5

3.5

Intragastric

Mean ± SE

80.8 ± 1.6

115.4 ± 5.2

113.4 ± 11.8

104.6 ± 9.6

98 ± 8.1

87.9 ± 3.9

86.3 ± 3.9

12,335* ± 655

43.1 ± 4.1

49 ± 4.2

44.7 ± 3.5

Median

80.5

120

123

115

100

92

86.5

12,845

38

47

40

Inter-quartile range

5.8

12.8

31.5

39.0

27.3

15.5

7.5

2198

10.5

9.0

6.5

  1. AUBGC area under the curve of blood glucose from starting to 120 min, s-AMY salivary α-amylase
  2. P < 0.05 (intragastric vs. control), paired t-test;  P < 0.05 (post- vs. pre-loading) and # P < 0.05 (60 min vs. post-loading), Wilcoxon signed-rank test; n = 7