Table 1 Toxicities associated with docetaxel/epirubicin chemotherapy for MA.22 patients in Schedules A or B
Toxicitiesa | Schedule A (N = 47) | Schedule B (N = 46) |
|---|---|---|
Febrile neutropenia | 6 (DLT Phase I) | 0 |
Fever | 1 | 0 |
Infections without neutropenia | 2 | 1 |
Fatigue | 1 | 7 (DLT Phase I) |
Muscle weakness | 0 | 1 |
Epistaxis | 0 | 1 |
Bleeding | 1 | 0 |
Pain | 1 | 5 |
Cardiac LVF | 0 | 1 |
Nausea/vomiting/diarrhea | 6 | 1 |
Dizziness/syncope/dehydration | 4 | 0 |
Neuropathy—sensory | 0 | 3 |