Table 2 Univariate and multivariate analysis of predictive factors for brain-progression-free survival (PFS)
From: The challenge of durable brain control in patients with brain-only metastases from breast cancer
Parameter | Median brain-PFS, months | Univariate (log-rank test) | Multivariate p value^ |
|---|---|---|---|
1–3 vs. >3 brain metastasesa | 10.8 vs. 4.6 | 0.13 | Not significant |
Cerebellar vs. not | 10.8 vs. 5.2 | 0.009 | 0.01 |
Cognitive deficit vs. none | 3.1 vs. 10.8 | 0.02 | 0.02 |
Coordination deficit vs. none | 4.6 vs. 6.9 | 0.06 | 0.01 |
KPS <80 vs. 80–100 | 2.1 vs. 8.9 | 0.13 | 0.009 |
Any systemic therapy vs. none (after local therapy for brain metastases) | 9.8 vs. 4.6 | 0.02 | Not significant |