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Table 1 Information on the studied plants

From: Antibacterial activities of Fagara macrophylla, Canarium schweinfurthii, Myrianthus arboreus, Dischistocalyx grandifolius and Tragia benthamii against multi-drug resistant Gram-negative bacteria

Plants samples (family) and Herbarium Voucher numbera

Part used and extraction yield (%)b

Area of plant collection

Traditional treatment

Bioactive (or potentially active) compounds isolated from plants

Biological activities of crude extractc

Canarium schweinfurthii Engl. (Burseraceae) 19652/HNC

Bark (7.36 %)

Bangangté, West Region of Cameroon

Insecticide, dysentery, gonorrhea, cough, chest pains, pulmonary affections, stomach complaints, food poisoning, purgative and emetic, roundworm infections and other intestinal parasites,emollient, stimulant, diuretic, skin-affections, eczema, leprosy, ulcers (Orwa et al. 2009); diabetes mellitus (Kouambou et al. 2007); colic, stomach pains, gale (Berhaut 1974); fever, constipation, malaria, sexual infection and rheumatism (Koudou et al. 2005)

Essential oil: limonene, phellandrenes (Orwa et al. 2009), triterpenes steroids, terpenoïdes, saponins, tannins, phenolics compounds, alkaloids (Kouambou et al. 2007; Tamboue et al. 2000)

Chemoprevention of cancer (Atawodi 2010); antimycobacterial activities (Nvau et al. 2011); antimicrobial activities against GIPAB (Moshi et al. 2009)

Dischistocalyx grandifolius C. B. Clarke (Acanthaceae) 27646/SRFC-Cam

Whole plant (4.53 %)

Bamboutos Mountain, West Region of Cameroon

Fungal and viral infections, cancer, inflammation, anti-pyretic, antioxidant, insecticidal, hepatoprotective, immunomodulatory, Anti- platelet aggregation (Awan and Aslam 2014)

Flavonoids, benzonoids, phenolic compounds, naphthoquinone and triterpenoids (Awan and Aslam 2014)

Not reported

Fagara macrophylla (Oliv.) Engl. (Rutaceae) 6173/SRFC-Cam

Leaves (6.81 %)

Bark (8.43 %)

Bamboutos Mountain, West region of Cameroon

Malaria (Zirihi et al. 2007); hypertension (Fézan et al. 2008)

Alkaloids: tembetarine,oblongine, magnoflorine, arborinine, nitidine (Torto and Mensah 1970; Tringali et al. 2001); dihydronitidine (Zirihi et al. 2007); acridone alkaloid and amide alkaloids (Wansi et al. 2009); flavonoid: hesperidin (Tringali et al. 2001)

Antiplasmodial activities of ethanol bark extracts (Zirihi et al. 2007); antifeedant activities of isolated acridone alkaloid, arborinine, tembetarine and magnoflorine against SF, SL, SFr (Tringali et al. 2001)

Myrianthus arboreus P. Beauv. (Moraceae) 55499/HNC

Bark (7.68 %)

Leaves (10.37 %)

Bangangté, West Region of Cameroon

Dysentery, diarrhea,vomiting; analgesic, antipyretic, heart troubles, pregnancy complications, dysmenorrheal, incipient hernia, boils, toothache, bronchitis, sore throat; headaches, swellings and tumours, diabete (Orwa et al. 2009);stomach disorders (Agwa et al. 2011; Uzodimma 2013)

Alkaloids, flavonoid, tannin (Orwa et al. 2009); cyanogenic glycosides, phytic acid (Agwa et al. 2011); terpenes (Borokini and Omotayo 2012); saponin, anthocyanin, glycoside, carotenoid, oxalate (Otitoju et al. 2014)

Antibacterial activities of methanol and aqueous extracts against KP, PV, SA, EC (Agwa et al. 2011); antiplasmodial activities by inhibiting the developmental stage of AG (Akinkurolere et al. 2011)

Tragia benthamii Bak. (Euphorbiaceae) 23329/SRFC-Cam

Whole plant (5.18 %)

Bangangté, West Region of Cameroon

Cough (Oladosu et al. 2013)

Tannins, saponins, flavonoids, alkaloids, (Oladosu et al. 2013)

Antimalarial activity (Oladosu et al. 2013)

  1. a(HNC): Cameroon National Herbarium; (SRF/Cam): Société des Réserves Forestières du Cameroun
  2. bThe percentage of the methanol extract
  3. cMicroorganisms [SF: Spodoptera frugiperda; SL: Spodoptera littoralis; SFr: Spodoptera frugiperda; KP: Klebsiella pneumoniae; PV: Proteus vulgaris; SA: Staphylococcus aureus; EC: Escherichia coli; AG: Anopheles gambiae; GIPB: gastrointestinal pathogenic bacteria]