Fig. 4

Cytopathic effects of the secretion on MCF-7 cells. A 5 × 10⁵ MCF-7 cells were seeded in a confocal dish, after the live-cell imaging began, the cells were treated with secretion. B SEM analysis of the MCF-7 and K562 cells after treatment with 10 µg/mL secretion from lamprey SB. Electron microscopy of MCF-7 or K562 cells treated for 30 min with 10 µg/mL secretion from lamprey SB cells