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Table 2 EBV copy numbers, serum antibodies, and expression of EBV mRNA

From: Production of thyrotropin receptor antibodies in acute phase of infectious mononucleosis due to Epstein–Barr virus primary infection: a case report of a child

 

July 25

August 27

September 24

3rd day

36th day

64th day

EBV copy number (/106 WBC)

4.1 × 103

4.2 × 103

2.6 × 103

EBV-EA-IgG (index*)

0.4 (−)

0.3 (−)

0.3 (−)

EBV-EBNA-IgG (index*)

0.1 (−)

0.2 (−)

1.9 (+)

EBV-VCA-IgM (index*)

1.5 (+)

0.6 (±)

1.4 (+)

EBV-VCA-IgG (index*)

1.1 (+)

6.6 (+)

8.9 (+)

Total-IgG (mg/ml)

11.15

13.37

9.49

Total-IgM (μg/ml)

836.2

815.05

825.1

Autoantibodies

 ANA (x)

(−)

(−)

(−)

 SMA (x)

(−)

(−)

(−)

 TRAbs (IU/l)

0.24

(−)

(−)

EBV mRNAs (copies/μgDNA)

 LMP1

(−)

(−)

(−)

 LMP2

(−)

(−)

(−)

 EBNA1

(−)

(−)

(−)

 EBNA2

4.29

(−)

(−)

 BZLF1

70.09

(−)

(−)

 EA-D

(−)

(−)

(−)

  1. Each value of mRNA is normalized to the expression of β-actin
  2. We used EBV mRNA from B95-8 strain as a reference
  3. EBV Epstein–Barr virus, EA early antigen, EBNA, Epstein–Barr nuclear antigen, VCA viral capsid antigen, LMP latent membrane protein, TRAbs thyrotropin receptor antibodies, SMA smooth muscle antibody, ANA antinuclear antibody
  4. * Index stands for sample absorbance/absorbance of cut-off serum