|
July 25
|
August 27
|
September 24
|
---|
3rd day
|
36th day
|
64th day
|
---|
EBV copy number (/106 WBC)
|
4.1 × 103
|
4.2 × 103
|
2.6 × 103
|
EBV-EA-IgG (index*)
|
0.4 (−)
|
0.3 (−)
|
0.3 (−)
|
EBV-EBNA-IgG (index*)
|
0.1 (−)
|
0.2 (−)
|
1.9 (+)
|
EBV-VCA-IgM (index*)
|
1.5 (+)
|
0.6 (±)
|
1.4 (+)
|
EBV-VCA-IgG (index*)
|
1.1 (+)
|
6.6 (+)
|
8.9 (+)
|
Total-IgG (mg/ml)
|
11.15
|
13.37
|
9.49
|
Total-IgM (μg/ml)
|
836.2
|
815.05
|
825.1
|
Autoantibodies
|
ANA (x)
|
(−)
|
(−)
|
(−)
|
SMA (x)
|
(−)
|
(−)
|
(−)
|
TRAbs (IU/l)
|
0.24
|
(−)
|
(−)
|
EBV mRNAs (copies/μgDNA)
|
LMP1
|
(−)
|
(−)
|
(−)
|
LMP2
|
(−)
|
(−)
|
(−)
|
EBNA1
|
(−)
|
(−)
|
(−)
|
EBNA2
|
4.29
|
(−)
|
(−)
|
BZLF1
|
70.09
|
(−)
|
(−)
|
EA-D
|
(−)
|
(−)
|
(−)
|
- Each value of mRNA is normalized to the expression of β-actin
- We used EBV mRNA from B95-8 strain as a reference
-
EBV Epstein–Barr virus, EA early antigen, EBNA, Epstein–Barr nuclear antigen, VCA viral capsid antigen, LMP latent membrane protein, TRAbs thyrotropin receptor antibodies, SMA smooth muscle antibody, ANA antinuclear antibody
- * Index stands for sample absorbance/absorbance of cut-off serum