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Table 1 Signal pattern [n (cell range %)] of ALK

From: Analysis of ALK gene in 133 patients with breast cancer revealed polysomy of chromosome 2 and no ALK amplification

 

Split pattern (1O1G1F)

Single orange (1O1F)

LCNG

HCNG

ER−/PR−/HER2− (n = 61)

1 (2 %)

12 (1–3 %)

39 (6–68 %)

1 (13 %)

ER−/PR−/HER2+ (n = 15)

0 (0 %)

3 (1–3 %)

12 (10–68 %)

1 (8 %)

ER+/PR±/HER2− (n = 37)

3 (2–3 %)

7 (1–12 %)

21 (6–69 %)

2 (6–11 %)

ER+/PR+/HER2+ (n = 20)

0 (0 %)

1 (1 %)

6 (6–91 %)

0 (0 %)

Inflammatory breast carcinoma (n = 13)

3 (2–3 %)

3 (5–12 %)

10 (9–69 %)

3 (6–13 %)

  1. 1O one orange signal (3′), 1G one green signal (5′), 1F one fusion signal (yellow), LCNG low copy number gains, HCNG high copy number gains
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