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Table 1 Signal pattern [n (cell range %)] of ALK

From: Analysis of ALK gene in 133 patients with breast cancer revealed polysomy of chromosome 2 and no ALK amplification

  Split pattern (1O1G1F) Single orange (1O1F) LCNG HCNG
ER−/PR−/HER2− (n = 61) 1 (2 %) 12 (1–3 %) 39 (6–68 %) 1 (13 %)
ER−/PR−/HER2+ (n = 15) 0 (0 %) 3 (1–3 %) 12 (10–68 %) 1 (8 %)
ER+/PR±/HER2− (n = 37) 3 (2–3 %) 7 (1–12 %) 21 (6–69 %) 2 (6–11 %)
ER+/PR+/HER2+ (n = 20) 0 (0 %) 1 (1 %) 6 (6–91 %) 0 (0 %)
Inflammatory breast carcinoma (n = 13) 3 (2–3 %) 3 (5–12 %) 10 (9–69 %) 3 (6–13 %)
  1. 1O one orange signal (3′), 1G one green signal (5′), 1F one fusion signal (yellow), LCNG low copy number gains, HCNG high copy number gains