Fig. 4From: Analysis of ALK gene in 133 patients with breast cancer revealed polysomy of chromosome 2 and no ALK amplificationLow copy number gain. A case of HER2+ breast cancer is shown revealing 3–6 ALK signals of ALK break-apart probes in representative tumor cells (open-head arrows). Normal signal pattern are seen in cells (arrowheads), as 2 ALK (yellow) signals with 2 CEP2 (aqua) signalsBack to article page