Fig. 2From: Blockade of the acute activation of mTOR complex 1 decreases hypertrophy development in rats with severe aortic valve regurgitationRapamycin inhibits mTORC1 but not mTORC2 LV activity in AR rats. LV protein content of total and phosphorylated forms of Akt, S6 kinase (S6K), S6 and 4EBP-1 in sham and AR rats treated or not with rapamycin. a, b Immunoblotting. c Gene expression of mTOR, S6 Kinase and Akt1 and Akt2. n = 9–12. Means not sharing a common superscript are significantly different from each other, P < 0.05Back to article page