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Fig. 1 | SpringerPlus

Fig. 1

From: Blockade of the acute activation of mTOR complex 1 decreases hypertrophy development in rats with severe aortic valve regurgitation

Fig. 1

Rapamycin reduces LV and RV hypertrophy and cardiac myocytes hypertrophy in AR rats. a LV and right ventricle (RV) weight after 8-week VO from AR and LV cardiac myocytes cross-sectional area (CSA) evaluated in mid-LV sections stained with Trichrome-Masson. b, c Representative Trichrome-Masson LV sections at different magnifications (b: bar = 1 cm and c: X200). For CSA, three sections per animals were analyzed and at least 20 myocytes per section measured by an observer blinded for the groups. n = 9–12. Means not sharing a common superscript are significantly different from each other, P < 0.05

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