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Table 1 Clinical profiles of 11 cases with high concentration of serum estradiol during TAM treatment

From: Tamoxifen-induced ovarian hyperstimulation during premenopausal hormonal therapy for breast cancer in Japanese women

Case Age Stage Chemo E2 (pg/mL) FSH (mIU/mL) Ns of follicles Estradiol/Ns (pg/mL) Av of Fl dia. (cm) Duration of TAM Tx (days) Status of mensus within 3 months
1 54 I   1556 4.4 2 778 2 364 Regular
2 46 I   1028 9.3 2 514 4.7 872 Regular
3 29 IIa Done 1600 9.9 4 400 2.5 889 Chemo-M
4 43 I   1202 8 4 300 2.5 1054 Regular
5 46 IIb Done 464 24.9 2 232 1.5 427 Chemo-M
6 30 IIIa Done 1081 12 2 540 2.7 137 Chemo-M
7 45 I   900 6.9 1 900 8.1 724 Regular
8 44 I   751 6 1 751 2.2 410 Irregular
9 36 IIa Done 898 7.7 1 898 4.3 791 Irregular
10 40 IIa Done 527 31.0 1 527 2.7 1825 Irregular
11 41 IIIc Done 1167 9.5 1 1,167 5 389 Chemo-M
  1. NAC neoadjuvant chemotherapy, Ns numbers, dia. diameters, E2 estradiol, Tx treatment, Fl follicular, Chemo chemotherapy, Chemo-M chemotherapy-induced menopause