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Table 1 Clinical profiles of 11 cases with high concentration of serum estradiol during TAM treatment

From: Tamoxifen-induced ovarian hyperstimulation during premenopausal hormonal therapy for breast cancer in Japanese women

Case

Age

Stage

Chemo

E2 (pg/mL)

FSH (mIU/mL)

Ns of follicles

Estradiol/Ns (pg/mL)

Av of Fl dia. (cm)

Duration of TAM Tx (days)

Status of mensus within 3 months

1

54

I

 

1556

4.4

2

778

2

364

Regular

2

46

I

 

1028

9.3

2

514

4.7

872

Regular

3

29

IIa

Done

1600

9.9

4

400

2.5

889

Chemo-M

4

43

I

 

1202

8

4

300

2.5

1054

Regular

5

46

IIb

Done

464

24.9

2

232

1.5

427

Chemo-M

6

30

IIIa

Done

1081

12

2

540

2.7

137

Chemo-M

7

45

I

 

900

6.9

1

900

8.1

724

Regular

8

44

I

 

751

6

1

751

2.2

410

Irregular

9

36

IIa

Done

898

7.7

1

898

4.3

791

Irregular

10

40

IIa

Done

527

31.0

1

527

2.7

1825

Irregular

11

41

IIIc

Done

1167

9.5

1

1,167

5

389

Chemo-M

  1. NAC neoadjuvant chemotherapy, Ns numbers, dia. diameters, E2 estradiol, Tx treatment, Fl follicular, Chemo chemotherapy, Chemo-M chemotherapy-induced menopause
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