Hemostatic effects of perioperative dDAVP. a Number and b weight of surgical pads used during the surgical procedure, as a function of the preoperative first dose of dDAVP (treatment groups 4 and 5 are presented together, since in both cases received 1 µg/kg). *p < 0.05 (1.0 versus 0.25 µg/kg), ANOVA with Tukey post-test. c vWF antigen (vWF:Ag) and d functional vWF (vWF:RCo) levels in samples collected prior to surgery (baseline), and after the preoperative dose (1st dDAVP dose) and the postoperative dose (2nd dDAVP dose). #p < 0.05 (2.0 µg/kg versus all other dose levels), two-way ANOVA with Tukey post-test. In all cases, data represent mean ± SEM.