Fig. 3

Roles of dendritic cells in the Cn pathogenesis. As most powerful antigen presenting cells, myeloid dendritic cells process and present Cn antigen to CD4⁺ T cells for the differentiation of cytotoxic Th1 cells. In contrast, plasmacytoid dendritic cells induce the non-protective Th2 cells. No evidence for the survival or death of Cn inside the plasmacytoid dendritic cells has been yet provided in the literature.