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Table 2 Clinical characteristics

From: Randomized sham controlled trial of cranial microcurrent stimulation for symptoms of depression, anxiety, pain, fatigue and sleep disturbances in women receiving chemotherapy for early-stage breast cancer

 

Sham (N = 81)

Active (N = 82)

Total (N = 163)

P-value

Surgery (count (%))

 Mastectomy

25 (31.25%)

29 (35.80%)

54 (33.54%)

0.28*

 Minimal surgery

29 (36.25%)

20 (24.69%)

49 (30.43%)

 

 Other

26 (32.50%)

32 (39.51%)

58 (36.02%)

 

Histology (count (%))

 IDC

76 (93.83%)

68 (82.93%)

144 (88.34%)

0.03**

 Other

5 (6.17%)

14 (17.07%)

19 (11.66%)

 

Grade (count (%))

 1

5 (6.17%)

6 (7.32%)

11 (6.75%)

0.95*

 2

32 (39.51%)

33 (40.24%)

65 (39.88%)

 

 3

44 (54.32%)

43 (52.44%)

87 (53.37%)

 

Stage (count (%))

 I

21 (25.93%)

16 (19.51%)

37 (22.70%)

0.25*

 IIA

31 (38.27%)

27 (32.93%)

58 (35.58%)

 

 IIB

15 (18.52%)

27 (32.93%)

42 (25.77%)

 

 IIIA

13 (16.05%)

12 (14.63%)

25 (15.34%)

 

 IIIB

1 (1.23%)

0 (0.00%)

1 (0.61%)

 

Chemotherapy (count (%))

 AC

4 (4.94%)

7 (8.75%)

11 (6.83%)

0.49*

 AC followed by Taxane

35 (43.21%)

29 (36.25%)

64 (39.75%)

 

 CMF

1 (1.23%)

0 (0.00%)

1 (0.62%)

 

 TC

31 (38.27%)

37 (46.25%)

68 (42.24%)

 

 Other

10 (12.35%)

7 (8.75%)

17 (10.56%)

 

Neoadjuvant

 Yes

26 (32.00%)

23 (28.00%)

49 (30.10%)

0.50**

 No

55 (68.00%)

59 (72.00%)

114 (69.90%)

 

Duration of chemotherapy (weeks)

15.93 ± 5.37

16.47 ± 5.42

16.20 ± 5.39

0.54*

Lymphnodes (count (%))

 Yes

35 (44.30%)

44 (53.66%)

79 (49.07%)

0.24**

 No

44 (55.70%)

38 (46.34%)

82 (50.93%)

 

Hormonal therapy (count (%))

 Yes

40 (51.95%)

48 (59.26%)

88 (55.70%)

0.36**

 No

37 (48.05%)

33 (40.74%)

70 (44.30%)

 

Estrogen receptor (count (%))

 Yes

42 (51.85%)

48 (58.54%)

90 (55.21%)

0.39**

 No

39 (48.15%)

34 (41.46%)

73 (44.79%)

 

HER2 NeuExpression (count (%))

 Yes

15 (18.52%)

24 (29.27%)

39 (23.93%)

0.11**

 No

66 (81.48%)

58 (70.73%)

124 (76.07%)

 

Progesterone receptor (count (%))

 Yes

34 (41.98%)

33 (40.24%)

67 (41.10%)

0.82**

 No

47 (58.02%)

49 (59.76%)

96 (58.90%)

 

LongActingOpiods (count (%))

 Yes

16 (19.75%)

19 (23.17%)

35 (21.47%)

0.60**

 No

65 (80.25%)

63 (76.83%)

128 (78.53%)

 

NonSteroidal analgesics (count (%))

 Yes

20 (24.69%)

10 (12.20%)

30 (18.40%)

0.04**

 No

61 (75.31%)

72 (87.80%)

133 (81.60%)

 

Anxiolytic (count (%))

 Yes

24 (29.63%)

17 (20.73%)

41 (25.15%)

0.19**

 No

57 (70.37%)

65 (79.27%)

122 (74.85%)

 
  1. * t-test.
  2. ** Chi-square test.