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Table 1 Baseline characteristics

From: Efficacy and safety of sitagliptin for the treatment of diabetes mellitus complicated by chronic liver injury

 

Total

Non LC

LC

NAFLD

ALD

C–CH

n

122

62

17

3

19

Age (years)

58.5 ± 13.9

55.9 ± 15.4

60.1 ± 10.9

53.6 ± 14.8

66.4 ± 8.7

Sex (male/female)

93/29

48/14

16/1

0/3

13/6

Duration of diabetes (years)

9.2 ± 7.5

8.0 ± 5.6

9.0 ± 6.9

10.3 ± 9.5

9.0 ± 4.8

BMI (kg/m2)

26.9 ± 5.4

28.0 ± 5.3

26.8 ± 5.4

29.3 ± 15.8

23.9 ± 2.8

Platelet (×104/μL)

18.3 ± 6.5

20.3 ± 5.7

19.0 ± 4.6

20.5 ± 6.6

9.3 ± 4.0

HbA1c (%)

8.48 ± 1.43

8.57 ± 1.23

8.29 ± 1.77

9.76 ± 2.70

8.12 ± 1.29

AST (IU/L)

56.0 ± 25.8

52.7 ± 25.3

66.5 ± 28.3

71.0 ± 26.2

60.4 ± 30.9

ALT (IU/L)

75.1 ± 45.2

79.2 ± 45.4

88.0 ± 67.4

94.0 ± 10.8

49.5 ± 28.4

γGT (IU/L)

155.2 ± 161.1

112.0 ± 80.4

232.8 ± 144.7

92.3 ± 47.4

277.6 ± 310.4

Duration of sitagliptin dosing (months)

13.7 ± 10.1

15.2 ± 10.0

10.6 ± 9.1

7.3 ± 6.6

9.1 ± 9.6

  1. The data represent the mean ± SD.
  2. AIH in 1 patient and unknown cause in 20 patients in addition to the data above.
  3. HbA1c hemoglobin A1c, AST aspartate aminotransferase, ALT alanin aminotransferase.