Skip to main content

Table 2 Demographics and clinical characteristics of the March 2010 and March 2012 cohort

From: Intra-operative hydroxyethyl starch is not associated with post-craniotomy hemorrhage

 

N = 1,247

N = 20

p value

No repeat craniotomy for post-operative hemorrhage

Repeat craniotomy for post-operative hemorrhage

Mean age, years (SD)

51.6 (16.3)

61.8 (14.8)

0.007

Male, n (%)

632 (50.7)

9 (45.0)

0.61

ASA grades 1–2, n (%)

488 (39.1)

2 (10.0)

0.008

ASA grades 3–5, n (%)

734 (58.9)

18 (90.0)

0.008

E Cases, n (%)

112 (9.0)

1 (5.0)

0.53

Tumor, n (%)

784 (62.9)

13 (65.0)

0.72

Vascular, n (%)

288 (23.1)

3 (15.0)

0.39

Trauma/other, n (%)

175 (14.0)

4 (20.0)

0.45

Baseline coagulopathy, n (%)

15 (1.2)

0 (0)

0.62

Mean EBL, mL (SD)

297.5 (345.2)

236.1 (157.7)

0.11

Mean operation length, min (SD)

212.1 (109.9)

197.7 (138.5)

0.65

Mean crystalloid volume, mL (SD)

2,390.5 (1,482.8)

2,683.8 (1,494.2)

0.39

Received plasmanate*, n (%)

202 (16.2)

2 (10.0)

0.45

Mean plasmanate* volume, mL (SD)

510.4 (288.8)

625 (176.8)

0.53

Received voluven, n (%)

142 (11.4)

2 (10.0)

0.85

Mean voluven volume, mL (SD)

664.4 (287.7)

750 (353.6)

0.67

Received PRBCs, n (%)

72 (5.8)

3 (15.0)

0.08

Mean PRBCs volume, mL (SD)

832.2 (893.4)

350 (0)

<0.001

Received FFP, n (%)

39 (3.1)

3 (15.0)

0.003

Mean FFP volume, mL (SD)

583.3 (605.1)

539.67 (68.7)

0.67

Received platelets, n (%)

38 (3.1)

2 (10.0)

0.08

Mean platelets volume, mL (SD)

360.1 (226.7)

249 (69.3)

0.5

  1. * Plasmanate is a purified plasma derivative consisting predominantly of human albumin.