From: Intra-operative hydroxyethyl starch is not associated with post-craniotomy hemorrhage
N = 1,247 | N = 20 | p value | |
---|---|---|---|
No repeat craniotomy for post-operative hemorrhage | Repeat craniotomy for post-operative hemorrhage | ||
Mean age, years (SD) | 51.6 (16.3) | 61.8 (14.8) | 0.007 |
Male, n (%) | 632 (50.7) | 9 (45.0) | 0.61 |
ASA grades 1–2, n (%) | 488 (39.1) | 2 (10.0) | 0.008 |
ASA grades 3–5, n (%) | 734 (58.9) | 18 (90.0) | 0.008 |
E Cases, n (%) | 112 (9.0) | 1 (5.0) | 0.53 |
Tumor, n (%) | 784 (62.9) | 13 (65.0) | 0.72 |
Vascular, n (%) | 288 (23.1) | 3 (15.0) | 0.39 |
Trauma/other, n (%) | 175 (14.0) | 4 (20.0) | 0.45 |
Baseline coagulopathy, n (%) | 15 (1.2) | 0 (0) | 0.62 |
Mean EBL, mL (SD) | 297.5 (345.2) | 236.1 (157.7) | 0.11 |
Mean operation length, min (SD) | 212.1 (109.9) | 197.7 (138.5) | 0.65 |
Mean crystalloid volume, mL (SD) | 2,390.5 (1,482.8) | 2,683.8 (1,494.2) | 0.39 |
Received plasmanate*, n (%) | 202 (16.2) | 2 (10.0) | 0.45 |
Mean plasmanate* volume, mL (SD) | 510.4 (288.8) | 625 (176.8) | 0.53 |
Received voluven, n (%) | 142 (11.4) | 2 (10.0) | 0.85 |
Mean voluven volume, mL (SD) | 664.4 (287.7) | 750 (353.6) | 0.67 |
Received PRBCs, n (%) | 72 (5.8) | 3 (15.0) | 0.08 |
Mean PRBCs volume, mL (SD) | 832.2 (893.4) | 350 (0) | <0.001 |
Received FFP, n (%) | 39 (3.1) | 3 (15.0) | 0.003 |
Mean FFP volume, mL (SD) | 583.3 (605.1) | 539.67 (68.7) | 0.67 |
Received platelets, n (%) | 38 (3.1) | 2 (10.0) | 0.08 |
Mean platelets volume, mL (SD) | 360.1 (226.7) | 249 (69.3) | 0.5 |