From: Intra-operative hydroxyethyl starch is not associated with post-craniotomy hemorrhage
N = 2,801 | N = 41 | p value | |
---|---|---|---|
No repeat craniotomy for post-operative hemorrhage | Repeat craniotomy for post-operative hemorrhage | ||
Mean age, years (SD) | 51.0 (16.0) | 54.6 (15.5) | 0.7 |
Male, n (%) | 1,322 (47.4) | 25 (62.5) | 0.06 |
ASA grades 1–2, n (%) | 1,236 (46.9) | 20 (50.0) | 0.82 |
ASA grades 3–5, n (%) | 1,152 (53.1) | 20 (50.0) | 0.82 |
E Cases, n (%) | 328 (12.1) | 2 (5.0) | 0.18 |
Tumor, n (%) | 1,393 (49.7) | 32 (80.0) | <0.0001 |
Vascular, n (%) | 305 (10.9) | 6 (15.0) | 0.23 |
Trauma/other, n (%) | 1,104 (39.5) | 2 (5.0) | <0.0001 |
Baseline coagulopathy, n (%) | 58 (2.1) | 1 (2.5) | 0.85 |
Mean EBL, mL (SD) | 279.1 (391.9) | 540.2 (1,176.2) | 0.16 |
Mean operation length, min (SD) | 229.2 (120.6) | 226.3 (159.5) | 0.15 |
Mean crystalloid volume, mL (SD) | 2,694.9 (1909.5) | 3,620.7 (2,351.1) | <0.0001 |
Received plasmanate*, n (%) | 420 (14.7) | 8 (19.5) | 0.38 |
Mean plasmanate* volume, mL (SD) | 529.7 (352.9) | 750 (353.6) | 0.21 |
Received hextend, n (%) | 185 (6.6) | 5 (12.5) | 0.15 |
Mean hextend volume, mL (SD) | 635.4 (286.9) | 650 (335.4) | 0.89 |
Received PRBCs, n (%) | 194 (6.9) | 3 (7.5) | 0.89 |
Mean PRBCs volume, mL (SD) | 877.5 (901.5) | 2,450 (1,603.9) | 0.003 |
Received FFP, n (%) | 82 (2.9) | 3 (7.5) | 0.09 |
Mean FFP volume, mL (SD) | 660.2 (603.0) | 1,227 (1,050.7) | 0.12 |
Received platelets, n (%) | 91 (3.2) | 1 (2.5) | 0.77 |
Mean platelets volume, mL (SD) | 353.0 (208.6) | 563 (–) | – |