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Figure 2 | SpringerPlus

Figure 2

From: Low-molecular-weight chitosan scavenges methylglyoxal and N ε-(carboxyethyl)lysine, the major factors contributing to the pathogenesis of nephropathy

Figure 2

Effects of lmw-chitosan on CEL concentrations in renal tissues of mice. A Immunostaining of CEL in the mouse kidney. a Control group (Group C); b mice induced by AA (10 mg kg−1 day−1) for 5 days (Group A); c lmw-chitosan-treated AAN mice (Group AM); and d normal mice treated with lmw-chitosan (Group M). CEL staining can be observed in the tubular region of monocytes (arrow). Nuclei were counterstained with hematoxylin. Original magnification: ×400 . B ELISA of CEL levels in mouse kidneys. Group C represents the control group. Group A was induced by AA (10 mg kg−1 day−1) for 5 days. Group AM represents lmw-chitosan-treated AAN mice. Group M consisted of normal mice treated with lmw-chitosan. It can be observed that CEL was increased by threefold in Group A, and that this effect was reversed in Group AM. *p < 0.05, compared to Group C; # p < 0.05, compared to the Group A, n = 5–6.

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