Figure 3From: The effect of anastrozole on bone mineral density during the first 5 years of adjuvant treatment in postmenopausal women with early breast cancerBMD changes of lumbar spine according to upfront, delayed or without Bis. In patients treated with upfront Bis (bold line; n = 19), 5.4% BMD increase from baseline was noted at the lumbar spine whereas in those without Bis (thin line; n = 21) BMD decreased by 4.3% from baseline within 24 months (p < 0.0001).Back to article page