Figure 5

Histopathological examination of biopsy of the skin lesion from the upper arm showing leukocytoclastic reaction. a, b Hematoxylin and Eosin staining showing the epidermis lined by keratinizing stratified squamous epithelium with evidence of spongiosis. Most of the blood vessels in underlying dermis showing thrombus formation along with necrosis in the vascular wall and neutrophilic infiltration. c, d Periodic acid schiff staining of the same skin lesions showing amorphus PAS positive material deposits (red arrows) in form of intramural and intravascular thrombus.