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Table 1 EC50 values for five test compounds with MDA-MB-231 cells

From: Altered cytotoxicity of ROS-inducing compounds by sodium pyruvate in cell culture medium depends on the location of ROS generation

 

Without pyruvate

With pyruvate

EC50 (μM)

95% confidence

EC50 (μM)

95% confidence

Alamethicin

2.0

1.9–2.2

2.5

2.4–2.7

Menadione

9.0

8.3–9.8

9.0

8.3–9.7

Eseroline

5.7

5.4–6.0

14.1

13.3–15.0

Benserazide

7.3

6.9–7.6

87.3

83.8–91.0

Pyrogallol

15.8a

None estimateda

153.6

148.1–159.2

  1. aDue to the steepness of the cytotoxicity curve, there was high uncertainty in the fit for this compound such that a 95% confidence interval was not estimated
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