Skip to main content
SpringerPlus

Table 5 Effect of Euryale ferox salisb. seeds extract (EFx) on hepatic enzymes in normal and STZ induced diabetic treated rats

From: Antidiabetic, antioxidant, antihyperlipidemic effect of extract of Euryale ferox salisb. with enhanced histopathology of pancreas, liver and kidney in streptozotocin induced diabetic rats

Groups

Biochemical parameters of hepatic enzymes

Hepatic hexokinase (units/min/mg of protein)

Gluocse-6-phosphatase (units/min/mg of protein)

Fructose 1-6-biphosphatase (units/min/mg of protein)

Glucose-6-phosphate dehydrogenase (units/min/mg of protein)

Normal rats [untreated with dimethylsulfoxide, (DMSO)] Group 1

0.2360 ± 0.007483a

0.0356 ± 0.0002449a

0.0320 ± 0.0004472a

0.1620 ± 0.003742a

Diabetic control (administered with Streptozotocin (STZ) Group 2

0.0880 ± 0.003742b

0.0646 ± 0.002249b

0.0664 ± 0.0009274b

0.0714 ± 0.0006782b

Diabetic + (EFx) (100 mg/kg body weight) Group 3

0.1080 ± 0.003742

0.0602 ± 0.0004899

0.0584 ± 0.0007483

0.0754 ± 0.0012080

Diabetic + (EFx) (200 mg/kg body weight) Group 4

0.1400 ± 0.003162

0.0548 ± 0.0005831

0.0526 ± 0.0014

0.0822 ± 0.00080000

Diabetic + (EFx) (300 mg/kg body weight) Group 5

0.1800 ± 0.003162

0.0464 ± 0.0009274

0.0466 ± 0.001030

0.08808 ±  0.01949

Diabetic + (EFx) (400 mg/kg body weight) Group 6

0.2024 ± 0.0006782**

0.0408 ± 0.0003742**

0.0376 ± 0.0005099***

0.1340 ± 0.0050990**

Diabetic + glibenclamide (1 mg/kg body weight) Group 7

0.2220 ± 0.003742***

0.0532 ± 0.001497**

0.0454 ± 0.002315**

0.1144 ± 0.003919**

  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons has been made by one way ANOVA followed by Dunnent’s test
  2. ns non-significant, STZ Streptozotocin.
  3. * p < 0.05 is considered as significant when compared to the control group (0 h).
  4. ** p < 0.001 is considered as very significant when compared to the control group (0 h).
  5. *** p < 0.001 is considered as extremely significant when compared to the control group (0 h).
  6. aCompared to diabetic control.
  7. bCompared to normal control.
Back to article page