Figure 9From: Antidiabetic, antioxidant, antihyperlipidemic effect of extract of Euryale ferox salisb. with enhanced histopathology of pancreas, liver and kidney in streptozotocin induced diabetic ratsEffect of Euryale ferox salisb seeds extract (EFx) on histological profile of pancreas in normal, STZ-induced diabetic untreated and STZ-induced diabetic treated wistar rats (original magnification ×10, DXIT 1200, Nikon, Japan). (1) NPAN: heamatoxylin and eosin (H/E) stained sections of pancreas of normal control rat portraying normal islet of langerhans shown by yellow arrows. (2) PSTZ: pancreatic section of streptozotocin induced diabetic rat showing no/destroyed islet of langerhans and beta cells depicted by red arrows. (3) PEFx-100: pancreatic section of STZ-induced diabetic rats treated with EFx at 100 mg/kg body weight showing small number of islet of langerhans (green arrows). (4) PEFx-200: section of pancreas of STZ-induced diabetic rats treated with EFx at 200 mg/kg body weight portraying increased number of islet of langerhans with small proportions of beta cells (green arrows). (5) PEFx-300: pancreas of diabetic rats treated with 300 mg/kg body weight. EFx depicting nearly normal islet of langerhans (green arrows). (6) PEFx-400: sections of pancreas of diabetic treated rats with 400 mg/kg body weight. EFx showing normal islet of langerhans with numerous beta cells (green arrows). (7) PGLIM: pancreatic section of diabetic rats treated with Glibenclamide showing normal pancreatic islet of langerhans with enhancement in the number of beta cells (dark yellow arrow).Back to article page