Changes in free amino acid and monoamine concentrations in the chick brain associated with feeding behavior

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Table 2 Changes in monoamine concentrations (pg/mg wet tissue) in the brain regions corresponding to feeding behavior in chicks

Monoamine	Diencephalon		Telencephalon		Mesencephalon		Cerebellum		Brain stem		P value
Monoamine	Hungry	Satiated	Hungry	Satiated	Hungry	Satiated	Hungry	Satiated	Hungry	Satiated	FB	BR	Interaction
DA	161 ± 4	140 ± 9	385 ± 4	339 ± 14	–	–	–	–	147 ± 18	146 ± 11	<0.05	<0.0001	NS
DOPAC	25 ± 3	18 ± 2	16 ± 3	14 ± 1	–	–	–	–	–	–	<0.05	<0.005	NS
HVA	119 ± 7	160 ± 10	89 ± 7	102 ± 5	34 ± 2	23 ± 1	17 ± 1	18 ± 1	2,181 ± 34	2,866 ± 56	<0.0001	<0.0001	<0.0001
NE	–	–	–	–	117 ± 3	199 ± 13	–	–	482 ± 42	322 ± 8	NS	<0.0001	<0.0001
5-HT	405 ± 13	380 ± 26	455 ± 11	436 ± 13	122 ± 11	207 ± 8	43 ± 1	39 ± 1	432 ± 36	338 ± 23	NS	<0.0001	<0.0005
5-HIAA	308 ± 27	321 ± 15	106 ± 5	130 ± 6	248 ± 8	156 ± 7	68 ± 2	63 ± 1	233 ± 24	350 ± 17	NS	<0.0001	<0.0001

Values are mean ± SEM. n = 7–8 in each group.
DA dopamine, DOPAC 3,4-dihydroxyphenylacetic, HVA homovanillic acid, NE norepinephrine, 5-HT serotonin, 5-HIAA 5-hydroxyindoleacetic acid, FB feeding behavior, BR brain region, NS not significant.