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Table 4 pCR is related to combination of CYP1B1 and ERCC1 polymorphisms

From: ERCC1 and CYP1B1 polymorphisms as predictors of response to neoadjuvant chemotherapy in estrogen positive breast tumors

CYP1B1 (Leu432Val)

ERCC1 (Asn118Asn)

N

pCR

OR

95% CI

P value

n

%a

CC

TT

19

2

10.5

1

Reference

 

CC

CT

22

11

50.0

8.5

(1.6–46)

0.013

CC

CC

6

1

16.7

1.7

(0.13–23)

0.69

CG

TT

15

1

6.7

0.61

(0.05–7.4)

0.70

CG

CT

20

2

10.0

0.94

(0.12–7.5)

0.96

CG

CC

10

2

20.0

2.1

(0.25–18)

0.49

GG

TT

6

1

16.7

1.7

(0.13–23)

0.69

GG

CT

8

3

37.5

5.1

(0.66–39)

0.12

GG

CC

7

2

28.6

3.4

(0.38–31)

0.28

  1. Significant results are shown in italic.
  2. pCR pathological complete response.
  3. a Percentages of evaluable patients.