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Table 3 pCR is related to 4 SNPs (N = 114)

From: ERCC1 and CYP1B1 polymorphisms as predictors of response to neoadjuvant chemotherapy in estrogen positive breast tumors

Gene SNP Genotype N pCR (N = 25) OR 95% CI P value
rs # wt n %a
BRCA1 rs799917 C CC 44 5 11.4 1   
Pro871leu   CT-TT 66 19 28.8 3.15 (1.08–9.2) 0.025
   NA 4 1     
SLCO1B3 rs11045585 A AA 79 13 16.5 1   
IVS12-5676   AG-GG 34 12 35.3 2.77 (1.10–6.7) 0.031
   NA 1 0     
CYP1B1 rs1056836 C CG 45 5 11.1 1   0.020
Leu432Val   CC-GG 69 20 29.0 3.26 (1.12–9.5)  
ERCC1 rs11615 T TT 40 4 10.0 1   
Asn118Asn   CT-CC 73 21 28.8 3.63 (1.15–11.5) 0.016
   NA 1 0     
  1. NA not applicable, pCR pathological complete response.
  2. aPercentages of evaluable patients.