| All Patients in Study | Close or Positive Margins | |||||
---|---|---|---|---|---|---|---|
Study (Author, Year) | Median follow-up | N | CWR rate | Margin definition | N | CWR rate | p value |
Current | 10.1 y | 1546 | 2.3% | Positive | 305 | 3.0% | 0.24 |
 |  |  |  | ≤2 mm | 220 | 1.4% | 0.84 |
Childs, 2013 [14] | 7.6 y | 142 | 1.4% | positive | 21 | 4.8% | Â |
 |  |  |  | ≤2 mm | 23 | 4.3% |  |
Owen, 2013 [6] | 12 y | 637 | 1.9% | Positive | 31 | 6.2% | NS |
 |  |  |  | <2 mm | 35 | 3.6% | NS |
Fitzsullivan, 2013 [8] | 6.3 y | 803 | 1% | <1 mm | 59 | 5.0% | <0.001 |
Chadha, 2012 [7] | 4.6 y | 211 | 0.9% | <1 mm | 24 | 8.3% | 0.013 |
Chan, 2011 [13] | 8 y | 193 | NR | Positive | 4 | 0 | Â |
Godat, 2009 [11] | 4.5 y | 83 | 1.1% | <2 mm | 20 | 0 | Â |
Rashtian, 2008 [12] | 61 m | 80 | 7.5% | <2 mm | 31 | 16.1% | 0.036 |
Carlson, 2007 [5] | 82.3 m | 223 | 5.1% | <1 mm | 19 | 10.5% | 0.32 |
Spiegel, 2003 [17] | 10.5 y | 44 | 0 | <1 mm | 6 | 0 | NS |