Figure 1From: Role of steroid hormones and morphine treatment in the modulation of opioid receptor gene expression in brain structures in the female ratExpression of Oprm1 gene in the striatum (a), hypothalamus (b), and PAG (c) in OVX female rats. The W group remained undisturbed. The SS group received saline solution 54 and 2 h before the experiments. The SM group received saline 54 h and 3.5 mg/kg morphine 2 h before the experiments. The ES group received estrogen (50 µg/kg, i.p.) 54 h before testing and saline 2 h before the experiments. The EM group received estrogen (50 µg/kg, i.p.) 54 h before testing and 3.5 mg/kg morphine 2 h before the experiments. *p < 0.05, compared with SS group. The data are expressed as mean ± SEM (ANOVA followed by Tukey’s multiple-comparison test).Back to article page