Table 2 Candidate causal pathways

1

Ephrin receptor binding

Interacting selectively and non-covalently with an ephrin receptor

<0.001

0.004

2

Hsa00983

Drug metabolism – other enzymes

<0.001

0.032

3

Hsa00240

Pyrimidine metabolism

0.004

0.032

4

Hsa00460

Cyanoamino acid metabolism

0.007

0.033

5

Growth

The increase in size or mass of an entire organism, a part of an organism or a cell

0.006

0.036

6

Kidney development

The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure

0.003

0.038

7

Cellular cation homeostasis

The regulation of the levels, transport, and metabolism of cations within a cell or between a cell and its external environment

0.009

0.039

8

Urogenital system development

The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure

<0.001

0.040

9

Lipid biosynthetic process

The chemical reactions and pathways resulting in the formation of lipids

0.006

0.040

10

Regulation of cell growth

Any process that modulates the frequency, rate or extent of cell growth

0.002

0.042

11

Hsa00500

Starch and sucrose metabolism

0.003

0.043

12

Cation homeostasis

The regulation of the levels, transport, and metabolism of cations

0.009

0.044