Table 1 Characteristics of documented cases of adult-onset dermatomyositis-associated panniculitis
Case no./Sex/ Age, y | Reference no. | Temporal relationship of panniculitis and dermatomyositis | Associated malignancy | Temporal relationship of panniculitis and malignancy | Number and location | Autoantibodies | Panniculitis features | Presence of calcinosis |
|---|---|---|---|---|---|---|---|---|
1/F/78y | (Lorenzo et al. 1998) | 5Â months earlier | no | - | N/A | N/A | N/A | N/A |
2/F/22y | (Weber and Gray 1924) | Concurrent | N/A | - | N/A | N/A | N/A | N/A |
3/F/44y | (Chao and Yang 2000) | 2.5Â months earlier | NS | - | Multiple/shoulders, back, chest, abdomen, buttock, and bilateral thighs | ANA 1:80 (speckled pattern) | NS | NS |
4/F/24y | (Winkelmann et al. 1990) | 4Â months earlier | no | - | Single/left arm | Negative | Lobular panniculitis with fat necrosis | NS |
5/F/42y | (Fusade et al. 1993) | 10Â months earlier | no | - | Multiple/buttocks, thighs, arms, abdomen, breasts | Negative | Lobular panniculitis with fat necrosis | NS |
6/F/23y | (Carneiro et al. 2007) | Later | no | - | Multiple/arms | ANA 1:40 (speckled pattern) | Lobular panniculitis, NS | NS |
7/M/19y | (Carrera et al. 2006) | 15Â months later | no | - | Several/left thigh | Negative | Lobular panniculitis resembling cytophagichistiocytic panniculitis | NS |
8/F/40y | (Feldman et al. 1983) | 1Â year later | NS | - | N/A | N/A | Septal panniculitis | NS |
9/F/54y | (Molnar et al. 1998) | Concurrent | no | - | Multiple/arms | Negative | Panniculitis, NS | NS |
10/F/57y | (Molnar et al. 1998) | Concurrent | no | - | Multiple/buttocks, left thigh and sacral | ANA 1:32 (nucleolar pattern) | Lobular panniculitis | NS |
11/F/60y | (Nakamori et al. 2003) | 8Â months earlier | no | - | Several/arms | ANA 1:640 | Lobular panniculitis | NS |
12/F/73y | (Abdul-Wahab et al. 2009) | 4Â months later | no | - | Multiple/anterior thighs and upper arms | NS | NS | yes |
13/F/50y | (Abdul-Wahab et al. 2009) | 18Â months later | NS | - | Multiple/extensor of all extremities | ANA (speckled pattern) | NS | yes |
14/F/29y | (Carneiro et al. 2007) | Concurrent | NS | - | Multiple/thighs | ANA 1:1024 (speckled pattern) | Lobular panniculitis with fat necrosis | yes |
15/M/42y | (Lee et al. 1999) | 1Â year earlier | no | - | Multiple/left buttock and left inguinal area | Negative | Fat necrosis with membranocystic change | yes |
16/F/42y | (Solans et al. 2002) | 17Â months later | no | - | Several/right and left upper elbow | Negative | Lobular necrotizing panniculitis | yes |
17/F/80y | (Solans et al. 2002) | 10Â months later | no | - | Single/right inner elbow | ANA 1:640 (speckled pattern) | Lipomembranous change | yes |
18/F/65y | (Ishikawa et al. 1996) | Concurrent | no | - | Multiple/buttocks, left thigh, lower right legs | Negative | Lipomembranous change | yes |
19/F/60y | (Carroll et al. 2014) | 2Â year later | NS | - | Multiple/thighs and buttocks | NS | Lobular fat necrosis with PMN infiltration | yes |
20/F/35y | (Lin et al. 2006) | 8Â months earlier | no | - | Multiple/right arm | Negative | Lipomembranous change | no |
21/F/56y | (Lin et al. 2006) | 2Â year after | Parotid carcinoma | NS | Multiple/arms | ANA 1:640 (speckled pattern) | Lipomembranous change | no |
22/M/51y | (Kuriya et al. 1985) | 14Â months earlier | Rhabdomyosarcoma | N/A | Single/buttock | Negative | Panniculitis with fat necrosis | N/A |
23/F/52y | (Leung et al. 2005) | Concurrent | Rectum carcinoma | NS | Multiple/thighs | NS | Lobular panniculitis, NS | NS |
24/F/63y | (Girouard et al. 2012) | 25Â months earlier | Ovarian cancer | Panniculitis developed 18Â years after diagnosis of malignancy | Multiple/arms and thighs | ANA 1:160 (speckled pattern) | Lobular panniculitis, NS | NS |
25/F/26y | Case report | 26Â months later | Nasopharyngeal cancer | Panniculitis developed 25Â months after diagnosis of malignancy | Multiple/extensor of all extremities, abdomen | ANA 1:320 (speckled pattern) | Lipomembranous change | yes |