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Table 2 Diagnostic performance of cardiac risk factors in percent (95% CI) for ACS within 30 days

From: Diagnostic values of chest pain history, ECG, troponin and clinical gestalt in patients with chest pain and potential acute coronary syndrome assessed in the emergency department

  Sensitivity Specificity LR+ LR-
Age (years)     
<40 0.3 (0.0-3.2) 82 (80–85) 0.02 (0.00-0.31) 1.2 (1.2- 1.2)
40-65 34 (27–42) 58 (55–61) 0.8 (0.6-1.0) 1.1 (1.0-1.3)
>65 66 (58–73) 60 (57–63) 1.6 (1.4-1.9) 0.6 (0.5-0.7)
>80 25 (19–33) 86 (84–88) 1.8 (1.3-2.5) 0.9 (0.8-1.0)
Risk factors     
Known PAD 4 (2–9) 98 (97–99) 2.0 (0.8-5.1) 1.0 (0.9-1.0)
Diabetes 29 (23–37) 88 (85–89) 2.4 (1.8-3.2) 0.8 (0.7- 0.9)
Previous stroke 16 (11–23) 92 (90–94) 2.1 (1.4-3.2) 0.9 (0.8-1.0)
Known CAD 51 (43–59) 74 (71–76) 2.0 (1.6-2.4) 0.7 (0.6-0.8)
Known heart failure 9 (5–15) 90 (88–91) 0.9 (0.5-1.5) 1.0 (1.0-1.1)
Male gender 75 (67–81) 47 (44–50) 1.4 (1.3-1.6) 0.5 (0.4- 0.7)
  1. LR, Likelihood ratio; PAD, peripheral artery disease; CAD, Coronary artery disease.