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Table 3 Deletions and multiplications

From: Genetic variability in the region encompassing reiteration VII of herpes simplex virus type 1, including deletions and multiplications related to recombination between direct repeats

Name a

Definition b

Pair of direct repeats c

No. of isolates

Del-1

Deletion of 27 bp (12237–12263), from the 16th residue of the 2nd element of reiteration VII to the 6th (the last) residue of the 4th element

CCGGGG

24

12231–12236

12258-12263

Del-2

Deletion of 45 bp (12219–12263), from the 16th residue of the 1st element of reiteration VII to the 6th (the last) residue of the 4th element

CCGGGG

23

12213–12218

12258-12263

Del-3

Deletion of 36 bp (12228–12263), from the 7th residue of the 2nd element of reiteration VII to the 6th (the last) residue of the 4th element

CCGGGG

1

12222–12227

12258-12263

Del-4

Deletion of 18 bp (12233–12250), from the 12th residue of the 2nd element of reiteration VII to the 11th residue of the 3rd element

GGGGAGACCGGGGCTCCC

12

12215–12232

12233-12250

Del-5

Deletion of 24 bp (12239–12262), from the 18th (the last) residue of the 2nd element of reiteration VII to the 5th residue of the 4th element

G

1

12238

12262

Del-6

Deletion of 27 bp (12219–12245), from the 16th residue of the 1st element of reiteration VII to the 6th residue of the 3rd element

CCGGGG

1

12213–12218

12240-12245

Mul-1

Duplication of 18 bp (12264–12281), from the 1st residue of the region surrounding the 4th element of reiteration VII

GGG

1

12216–12218

12279-112281

Mul-2

Duplication of 18 bp (12215–12218, 12264–12277), from the 12th residue of the 1st element of reiteration VII

TCCC

16

12211–12214

12274-12277

Mul-3

Triplication of 18 bp (12215–12218, 12264–12277), from the 12th residue of the 1st element of reiteration VII

TCCC

1

12211–12214

12274-12277

Mul-4

Tetraplication of 18 bp (12215–12218, 12264–12277), from the 12th residue of the 1st element of reiteration VII

TCCC

1

12211–12214

12274-12277

  1. aSix kinds of deletions were found on the nucleotide sequences encompassing reiteration VII relative to those of strain 17, and were named del-1 to del-6. Four kinds of multiplications were found on the nucleotide sequences encompassing reiteration VII relative to those of strain 17, and named mul-1 to mul-4.
  2. bThe nucleotide numbering system used was a short unique region of HSV-1 strain 17 (McGeoch et al. 1985).
  3. cThe nucleotide sequences of each pair of direct repeats, which were assumed to be involved in the generation of deletions or multiplications, and the nucleotide no. of each pair were indicated.