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Figure 2

From: Genetic variability in the region encompassing reiteration VII of herpes simplex virus type 1, including deletions and multiplications related to recombination between direct repeats

Figure 2

Involvement of a pair of direct repeats in the generation of deletions or multiplications. Direct repeats on the region encompassing reiteration VII were indicated by horizontal arrows, and the stretch flanked by a pair of direct repeats was indicated by a double line. (a) Generation of del-2. The misalignment of direct repeats (CCGGGG) during DNA replication indicated by a broken line could result in the generation of the deletion of del-2. (b) Generation of mul-2. The misalignment of direct repeats (TCCC) during DNA replication indicated by a broken line could result in the generation of the multiplication of mul-2 (duplication). Each copy of the duplicated sequences was indicated by a solid line having a closed circle at both ends.

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