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Table 2 Number of off-label drugs and encounters for each drug category and subcategory

From: Off-label use of cancer therapies in women diagnosed with breast cancer in the United States

Category Number off-label drugs (%) 1 Off-label encounters (%) 2 Subcategories Number Off-label drugs (%) 2 Off-label encounters (%) 2
Chemotherapies 24 (55.8%) 1153 (14.1%) Topoisomerase inhibitor 4 (100%) 61 (27.9%)
    Alkylating agents 7 (58.3%) 485 (26.2%)
    Anti-metabolites 8 (61.5%) 103 (8.5%)
    Anti-tumor antibiotics 3 (37.5%) 75 (6.3%)
    Anti mitotics 2 (28.6%) 429 (11.6%)
Other agents 12 (54.5%) 483 (8.4%) Targeted therapies 2 (50.0%) 11 (37.9%)
    Immunotherapies 5 (45.5%) 233 (8.2%)
    Hormone therapies 5 (62.5%) 239 (8.2%)
  1. 1Expressed as a percentage of all drugs including those indicated for breast cancer in a given therapeutic category or subcategory.
  2. 2Expressed as a percentage of all encounters including those indicated for breast cancer in a given therapeutic category or subcategory.