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Table 2 Number of off-label drugs and encounters for each drug category and subcategory

From: Off-label use of cancer therapies in women diagnosed with breast cancer in the United States

Category

Number off-label drugs (%) 1

Off-label encounters (%) 2

Subcategories

Number Off-label drugs (%) 2

Off-label encounters (%) 2

Chemotherapies

24 (55.8%)

1153 (14.1%)

Topoisomerase inhibitor

4 (100%)

61 (27.9%)

   

Alkylating agents

7 (58.3%)

485 (26.2%)

   

Anti-metabolites

8 (61.5%)

103 (8.5%)

   

Anti-tumor antibiotics

3 (37.5%)

75 (6.3%)

   

Anti mitotics

2 (28.6%)

429 (11.6%)

Other agents

12 (54.5%)

483 (8.4%)

Targeted therapies

2 (50.0%)

11 (37.9%)

   

Immunotherapies

5 (45.5%)

233 (8.2%)

   

Hormone therapies

5 (62.5%)

239 (8.2%)

  1. 1Expressed as a percentage of all drugs including those indicated for breast cancer in a given therapeutic category or subcategory.
  2. 2Expressed as a percentage of all encounters including those indicated for breast cancer in a given therapeutic category or subcategory.