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Table 1 Crude and adjusted hazard ratios (HR) with 95 % confidence interval (CI) for methotrexate restart after a treatment gab ≥ 90 days among 299 patients with rheumatoid arthritis in the County of Aarhus, Denmark 1998-2006

From: Methotrexate utilization in Rheumatoid arthritis. A register-based cohort-study of treatment re-starts after gabs of at least 90 days

Gender Male 203 (67.9) 1.3 (0.9;1.9) 1.3 (0.9;2.0)
Female 96 (32.1) 1 1
Age <55 years 109 (36.5) 0.8 (0.5;1.3) 0.9 (0.6;1.7)
55-67 years 92 (30.7) 1 1
>67 years 98 (32.8) 0.7 (0.4;1.1) 0.7 (0.4;1.2)
C-reactive protein < 75 nmol/L 154 (51.5) 1 1
76-300 nmol/L 78 (26.1) 1.0 (0.6;1.5) 1.1(0.7;1.8)
>300 nmol/L 60 (20.1) 0.5 (0.3;0.9) 0.6 (0.3;1.2)
Missing 7 (2.3) - -
Hemoglobin Low 89 (29.8) 1.4 (0.9;2.2) 1.0 (0.6;1.8)
Normal 203 (67.9) 1 1
Missing 7 (2.3) - -
Co-morbidity 0 209 (69.9) 1 1
  > = 1 90 (30.1) 0.8 (0.5;1.2) 0.8 (0.5;1.3)
Concurrent DMARD Yes 110 (36.8) 0.7 (0.5;1.0) 0.8 (0.5; 1.2)
No 189 (63.2) 1 1
Corticosteroids Yes 100 (33.4) 0.5 (0.3,0.7) 0.7 (0.4;1.1)
No 189 (66.6) 1 1