Differentiation of extranodal non-Hodgkins lymphoma from squamous cell carcinoma of the maxillary sinus: a multimodality imaging approach

SpringerPlus

Table 2 Qualitative imaging findings and quantitative measurements with NHL and SCC of maxillary sinus

	NHL	SCC	p value
Qualitative Imaging Findings on CT	(n = 12)	(n = 29)
Predominant growth pattern
Permeative	6 (50)^a	3 (10)
Destructive	4 (33)	24 (83)^aa
Expansile	2 (17)	2 (7)
Remaining sinus wall within the tumor	11 (92)^a	10 (34)	0.001
Intratumoral necrosis	2 (17)	25 (86)^aa	< 0.001
Cervical lymphadenopathy	4 (33)	4 (14)	0.158
Tumor extension
Nasal cavity	9 (75)	22 (76)	0.622
Orbit	6 (50)	19 (66)	0.281
Subcutaneous tissue	9 (75)	17 (59)	0.266
Retroantral fat pad	10 (83)	24 (83)	0.672
Pterygoid process	2 (17)	10 (34)	0.226
Perineural spread	1 (8)	6 (21)	0.323
Intracranial	1 (8)	3 (10)	0.668
Quantitative Measurements on MRI	(n = 4)	(n = 17)
T1–weighted images	0.89 ± 0.09	0.96 ± 0.18	0.457
T2–weighted images	1.10 ± 0.21	1.07 ± 0.25	0.813
Diffusion-weighted images	1.64 ± 0.68	1.13 ± 0.31	0.227
ADC (×10⁻³ mm²/s)	0.61 ± 0.09^aaa	0.95 ± 0.12	< 0.001
Quantitative Measurements on PET/CT	(n = 7)	(n = 15)
SUVmax	20.8 ± 7.4	17.4 ± 5.4	0.517

Note.-- NHL = non-Hodgkin lymphoma, SCC = squamous cell carcinoma. In qualitative imaging findings, data are numbers of patients, and numbers in parentheses are frequencies expressed as percentages. In quantitative measurements, deta are signal intensity ratio, ADC value, and SUVmax, with the mean ± 1 standard deviation
^aThe frequency of NHL was significantly greater than that of SCC (p < 0.01)
^aaThe frequency of SCC was significantly greater than that of NHL (p < 0.01)
^aaaThe value of NHL was significantly lower than that of SCC (p < 0.01)