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Table 1 In vitro cytotoxicity of IMTXA33αS, wild type α-sarcin and scFvA33

From: Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts

	GPA33 (+)		GPA33 (−)
	SW1222	LIM1215	HT29	A431
IMTXA33αS	0.03*	0.07	> > 1.00*	> > 1.00*
α-Sarcin	0.8*	> 1.00	> > 1.00*	1.00*
scFvA33	NM	NM	NM	NM

*, (Carreras-Sangrà et al. 2012); NM, too high to be measurable.
IC₅₀ (protein concentration inhibiting 50% of protein biosynthesis) (μM) obtained for the cell lines assayed, after 72 h of incubation with the different proteins.

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