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Figure 4 | SpringerPlus

Figure 4

From: Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts

Figure 4

IMTXA33αS-treated tumors show inhibition of cancer cell proliferation and induction of cancer cell apoptosis in vivo . A) Ki67-positive cells (green) and B) active caspase-3-positive cells (green) in tumors. Scale bars: A, 60 μm; B, 60, 30, 40 μm (from left to right). C) Quantification of Ki67-positive cells (A) and active-caspase-3-positive cells (B) in the tumors are shown in the corresponding graphs. Statistical analysis of IMTX50 or IMTX100-treated tumors vs vehicle-treated tumors rendered p < 0.001 (A) and p < 0.05 (B).

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