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Figure 3

From: Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts

Figure 3

IMTXA33 α S impaired angiogenesis on in vivo treated tumors. A) Representative images of the excised remaining tumors of non-treated (PBS) or treated (IMTX50, IMTX100) experimental groups. Scale is in centimeters. Each column shows three examples from each group. B) CD31-positive cells (red). Scale bars: 60 μm. Quantification of the number of blood vessels is shown in the corresponding graph. Statistical analysis of IMTX50 or IMTX100-treated tumors vs vehicle-treated tumors rendered p <0001.

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