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Table 3 Dosimetric comparison of Standard IMRT plan, Sparing IMRT plan and VMAT planfor PTV 46 and 60 plans

From: Comparison of dose distributions hippocampus in high grade gliomas irradiation with linac-based imrt and volumetric arc therapy: a dosimetric study

 

Standard IMRT plan

Sparing IMRT plan

VMAT plan

p value

PTV46 max dose (Gy)

46.9 (46.2-47.4)

47 (46.5-47.6)

47.5 (48.5-50.1)

0.14

PTV46 mean dose (Gy)

48.9 (48-50.4)

49.3 (48.3-50.8)

48.5 (47.9-50.4)

0.21

D 95 46 (Gy) mean SD

46 (45.7-46.3)

46 (45.8-46.3)

46.4 (45.8-46.8)

0.55

PTV60 max dose (Gy)

63.2 (60.7-62.2)

63.4 (60.7-62.1)

63.6 (61.2-62.6)

0.44

PTV60 mean dose (Gy)

61 (61-64.3)

61.2 (62.4-64.9)

61.4 (61.3-64.6)

0.23

D 95 60 (Gy)

60 (59.7-60.2)

60 (59.9-60.3)

60 (59.9-61.5)

0.65

HI (60 Gy)

1.03 (1.02-1.05)

1.03 (1.02-1.04)

1.03 (1.02-1.04)

0.34

CI (60 Gy)

1.2 (1-1.4)

1.2 (1.1-1.6)

1.2 (0.9-1.6)

0.48

MU (0-60 Gy)

1472 (1041-1834)

1320 (1116-1993)

994 (886-1150)

0.01

Right lens max

4.8 (2.5-9.3)

5.2 (2.8-9.3)

7.5 (4.1-10.8)

0.1

Left lens max

7.7 (4.6-10.3)

6.1 (3.8-9.8)

4.0 (3.7-9.9)

0.001

Right eye mean

8.3 (4-25.8)

9.4 (5.1-16.7)

10.3 (3.6-17.6)

0.45

Left eye mean

10.8 (4.2-19.7

9.4 (6.2-16.2)

8.4 (5.9-16.3)

0.023

Right optic nerve max

35.1(29.2-41.0)

35.7 (30.6-40.8)

32.2 (25.2-39.1

0.65

Left optic nerve max

36.1 (30.2-42.1)

37.9 (32.4-43.5)

33.2 (25.6-40.8)

0.55

Optic chiasm max

39.8 (33.7-45.6)

43.2 (37.9-48.5)

37 (29.6-45.2)

0.7

Brainstem max

51.1 (48.2-54.3)

50.9 (48.3-54.5)

50.1 (48.9-54.1)

0.44