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Table 3 Baseline characteristics metastatic melanoma

From: Clinical characteristics and treatment-related biomarkers associated with response to high-dose interleukin-2 in metastatic melanoma and renal cell carcinoma: retrospective analysis of an academic community hospital’s experience

 

Clinical benefit (n=8)

No clinical benefit (n=29)

P-value

Age

54.5 (49.0-59.25)

56.0 (43.5-64.5)

.986*

Male

8 (100%)

22 (75.9%)

.308

BRAF Mutated

2/5 (40%)

9/19 (47.4%)

1.00

Baseline ALC

1.50 (0.975-1.775)

1.30 (0.95-1.80)

.842*

LDH

203.5 (164.0-415.75)

244.0 (187.0-542.5)

.251*

Ulceration

2/6 (33.3%)

6/20 (30.0%)

1.00

Prior Treatments

0/8 (0%)

7/29 (24.1%)

0.318

Metastatic Subsets

IVA

2 (25%)

4 (13.8%)

.591

IVB

1 (12.5%)

6 (20.7%)

1.0

IVC

5 (62.5%)

19 (65.5%)

1.0

  1. Fisher’s Exact test (reported as frequency(percent)).
  2. * Mann–Whitney U (reported as median (interquartile range)).
  3. ALC: Absolute Lymphocyte Count.
  4. LDH: Lactate Dehydrogenase.