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Table 3 SNPs from the haplotype analysis with ORs and p -values for breast cancer association

From: RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families

Gene rs-number HGVS MAF controls MAF cases OR 95% CI p- value
RAD51 rs1801320 c.-98G > C 0.09 0.07 0.82 0.66-1.01 0.184
RAD51 rs3092981 c.-3 + 102C > T 0.17 0.18 1.07 0.91-1.27 0.614
RAD51 rs5030791 c.-3 + 203G > T 0.03 0.02 0.83 0.59-1.18 0.583
RAD51 rs2619681 c.-3 + 1398 T > C 0.18 0.17 0.88 0.75-1.05 0.352
RAD51 rs2304579 c.87 + 110A > G 0.09 0.07 0.82 0.67-1.01 0.184
RAD51 rs4924496 c.225 + 1936 T > C 0.29 0.29 1.06 0.90-1.24 0.549
RAD51 rs45503494 c.343 + 494 T > C 0.09 0.07 0.82 0.67-1.02 0.205
RAD51 rs45455000 c.344-36 T > G 0.09 0.07 0.82 0.67-1.02 0.202
RAD51 rs12592524 c.435 + 2149G > A 0.30 0.30 1.07 0.91-1.25 0.518
RAD51 rs4144242 c.436-4016G > A 0.09 0.07 0.82 0.67-1.02 0.202
RAD51 rs4924500 c.530 + 4654A > G 0.18 0.17 0.88 0.74-1.04 0.314
RAD51 rs45532539 c.531-3201G > T 0.004 0.009 1.92 0.97-4.10 0.062
RAD51 rs45507396 c.*929A > G 0.09 0.07 0.82 0.66-1.01 0.187
RAD51 rs45585734 c.*1113C > G 0.09 0.07 0.82 0.66-1.01 0.187
XRCC3 rs861539 c.722C > T 0.32 0.33 1.06 0.90-1.24 0.489
XRCC3 rs861537 c.562-1162G > A 0.29 0.26 0.89 0.76-1.04 0.060
XRCC3 rs861536 c.562-1651 T > C 0.32 0.33 1.06 0.90-1.24 0.475
XRCC3 rs12432907 c.561 + 1132G > A 0.23 0.21 0.92 0.78-1.08 0.092
XRCC3 rs3212092 c.561 + 866C > T 0.004 0.002 0.57 0.20-1.51 0.246
XRCC3 rs3212081 c.407-478G > A 0.005 0.006 1.15 0.55-2.49 0.704
XRCC3 rs3212079 c.407-801C > T 0.04 0.04 0.97 0.73-1.28 0.951
XRCC3 rs861531 c.406 + 533G > T 0.32 0.33 1.06 0.90-1.24 0.459
XRCC3 rs3212042 c.56-652G > A 0.03 0.04 1.17 0.86-1.58 0.456
XRCC3 rs3212028 c.-261 + 1368G > A 0.11 0.11 1.07 0.88-1.29 0.427
XRCC2 rs3218552 c.*1874G > A 0.02 0.02 0.95 0.66-1.37 0.879
XRCC2 rs3218550 c.*1772G > A 0.02 0.02 1.07 0.74-1.55 0.729
XRCC2 rs3218536 c.563G > A 0.04 0.05 1.08 0.82-1.43 0.256
XRCC2 rs3218504 c.122-4868C > T 0.02 0.02 0.94 0.65-1.36 0.878
XRCC2 rs6964582 c.122-5014G > C 0.02 0.02 1.02 0.70-1.47 0.676
XRCC2 rs3218501 c.122-5469C > G 0.02 0.02 0.93 0.64-1.34 0.839
XRCC2 rs3218491 c.121 + 4038A > G 0.02 0.02 1.04 0.72-1.52 0.817
XRCC2 rs3111465 c.40-4608 T > C 0.02 0.02 1.02 0.70-1.48 0.676
XRCC2 rs3094406 c.40-4998G > C 0.04 0.05 0.99 0.76-1.30 0.252
XRCC2 rs3218408 c.39 + 5510 T > G 0.23 0.23 1.09 0.93-1.28 0.447
  1. The SNPs are presented in the same order as in the haplotypes in Table 2.