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Table 1 Clinicopathologic characteristics of 325 women with lymph node-positive breast cancer according to lymph node ratio (LNR)

From: Prognostic value of the lymph node ratio for lymph-node-positive breast cancer- is it just a denominator problem?

Characteristic		Lymph node ratio
		Low-risk		Intermediate-risk		High-risk		All
		(≤0.20)		(>0.20 & ≤0.65)		(>0.65)		All
		(n = 187)		(n = 99)		(n = 39)		(n = 325)
	P value	No.	(%)	No.	(%)	No.	(%)	No.	(%)
Age, yrs	0.622
<40		22	11.8	8	8.1	3	7.7	33	10.2
≥40		165	88.2	91	91.9	36	92.3	292	89.8
Tumour size, mm	<0.001
0–20		110	58.8	33	33.3	13	33.3	156	48.0
>20		77	41.2	66	66.7	26	66.7	169	52.0
Histological grade	0.063
1	(0.047)	30	16.0	8	8.1	4	10.3	42	12.9
2		74	39.6	40	40.4	8	20.5	122	37.5
3		68	36.4	43	43.4	21	53.8	132	40.6
Unknown		15	8.0	8	8.1	6	15.4	29	8.9
ER status	0.362
Negative	(0.869)	15	8.0	7	7.1	2	5.1	24	7.4
Positive		48	25.7	16	16.2	7	17.9	71	21.8
Unknown		124	66.3	76	76.8	30	76.9	230	70.8
No. of nodes removed	0.249
6–10		30	16.0	26	26.3	7	17.9	63	19.4
11–15		64	34.2	35	35.4	14	35.9	113	34.8
>15		93	49.7	38	38.4	18	46.2	149	45.8
pN stage	<0.001
pN1 (1–3)		182	97.3	28	28.3	0	0.0	210	64.6
pN2 (4–9)		5	2.7	58	58.6	11	28.2	74	22.8
pN3 (≥10)		0	0.0	13	13.1	28	71.8	41	12.6
Radiation therapy	0.001
No		125	66.8	45	45.9	18	46.2	188	58.0
Yes		62	33.2	53	54.1	21	53.8	136	42.0
Chemotherapy	0.007
No		92	50.3	30	30.9	15	39.5	137	43.1
Yes		91	49.7	67	69.1	23	60.5	181	56.9
Hormone therapy	0.278
No		79	42.2	33	33.3	13	33.3	125	38.5
Yes		108	57.8	66	66.7	26	66.7	200	61.5

P values are for comparison of categories of each variable by lymph node ratio using the Pearson chi-square test or the Fisher exact test. For characteristics with an unknown category the P values without unknown category are shown within parentheses. Patients with > 5 nodes removed included in the table.
Missing values: Radiation therapy = 1, Chemotherapy = 7.

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