Characteristic | Â | Lymph node ratio | |||||||
---|---|---|---|---|---|---|---|---|---|
 |  | Low-risk | Intermediate-risk | High-risk | All | ||||
(≤0.20) | (>0.20 & ≤0.65) | (>0.65) | |||||||
 |  | (n = 187) | (n = 99) | (n = 39) | (n = 325) | ||||
 | P value | No. | (%) | No. | (%) | No. | (%) | No. | (%) |
Age, yrs | 0.622 | Â | Â | Â | Â | Â | Â | Â | Â |
<40 | Â | 22 | 11.8 | 8 | 8.1 | 3 | 7.7 | 33 | 10.2 |
≥40 |  | 165 | 88.2 | 91 | 91.9 | 36 | 92.3 | 292 | 89.8 |
Tumour size, mm | <0.001 | Â | Â | Â | Â | Â | Â | Â | Â |
0–20 |  | 110 | 58.8 | 33 | 33.3 | 13 | 33.3 | 156 | 48.0 |
>20 | Â | 77 | 41.2 | 66 | 66.7 | 26 | 66.7 | 169 | 52.0 |
Histological grade | 0.063 | Â | Â | Â | Â | Â | Â | Â | Â |
1 | (0.047) | 30 | 16.0 | 8 | 8.1 | 4 | 10.3 | 42 | 12.9 |
2 | Â | 74 | 39.6 | 40 | 40.4 | 8 | 20.5 | 122 | 37.5 |
3 | Â | 68 | 36.4 | 43 | 43.4 | 21 | 53.8 | 132 | 40.6 |
Unknown | Â | 15 | 8.0 | 8 | 8.1 | 6 | 15.4 | 29 | 8.9 |
ER status | 0.362 | Â | Â | Â | Â | Â | Â | Â | Â |
Negative | (0.869) | 15 | 8.0 | 7 | 7.1 | 2 | 5.1 | 24 | 7.4 |
Positive | Â | 48 | 25.7 | 16 | 16.2 | 7 | 17.9 | 71 | 21.8 |
Unknown | Â | 124 | 66.3 | 76 | 76.8 | 30 | 76.9 | 230 | 70.8 |
No. of nodes removed | 0.249 | Â | Â | Â | Â | Â | Â | Â | Â |
6–10 |  | 30 | 16.0 | 26 | 26.3 | 7 | 17.9 | 63 | 19.4 |
11–15 |  | 64 | 34.2 | 35 | 35.4 | 14 | 35.9 | 113 | 34.8 |
>15 | Â | 93 | 49.7 | 38 | 38.4 | 18 | 46.2 | 149 | 45.8 |
pN stage | <0.001 | Â | Â | Â | Â | Â | Â | Â | Â |
pN1 (1–3) |  | 182 | 97.3 | 28 | 28.3 | 0 | 0.0 | 210 | 64.6 |
pN2 (4–9) |  | 5 | 2.7 | 58 | 58.6 | 11 | 28.2 | 74 | 22.8 |
pN3 (≥10) |  | 0 | 0.0 | 13 | 13.1 | 28 | 71.8 | 41 | 12.6 |
Radiation therapy | 0.001 | Â | Â | Â | Â | Â | Â | Â | Â |
No | Â | 125 | 66.8 | 45 | 45.9 | 18 | 46.2 | 188 | 58.0 |
Yes | Â | 62 | 33.2 | 53 | 54.1 | 21 | 53.8 | 136 | 42.0 |
Chemotherapy | 0.007 | Â | Â | Â | Â | Â | Â | Â | Â |
No | Â | 92 | 50.3 | 30 | 30.9 | 15 | 39.5 | 137 | 43.1 |
Yes | Â | 91 | 49.7 | 67 | 69.1 | 23 | 60.5 | 181 | 56.9 |
Hormone therapy | 0.278 | Â | Â | Â | Â | Â | Â | Â | Â |
No | Â | 79 | 42.2 | 33 | 33.3 | 13 | 33.3 | 125 | 38.5 |
Yes | Â | 108 | 57.8 | 66 | 66.7 | 26 | 66.7 | 200 | 61.5 |