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Table 2 Effects of bafilomycin A1 on bone resorption in rabbit bone cells culture

From: Induction of creatine kinase release from cultured osteoclasts via the pharmacological action of aminobisphosphonates

Treatment Concentration of minodronic acid (μmol/L) CTX-1 concentration (nmol/L)
Without bafilomycin A1 With bafilomycin A1
Control - 265.0 ± 19.2 3.0 ± 0.6*
Minodronic acid 0.3 50.9 ± 4.3# 3.2 ± 0.4*
1 14.0 ± 1.4# 2.4 ± 0.5*
3 6.2 ± 1.1# 2.5 ± 0.3*
  1. Values represents the mean ± SE of 10 individual cultures.
  2. #Significantly different from bafilomycin A1 untreated control (p < 0.05).
  3. *Significantly different from corresponding bafilomycin A1 untreated group (p < 0.05).