Table 1 Patient demographics and characteristics
No. of patients (%) | |||||
|---|---|---|---|---|---|
Variable | All patients, N = 308 | Low RS (<18), N = 160 | Intermediate RS (18–30), N = 123 | High RS (>30), N = 25 | P -value |
Median age at diagnosis, y (range) | 54 (30–78) | 53 (31–78) | 55 (30–73) | 59 (40–75) | NS |
Frequency by race | NS | ||||
Asian/Pacific Islander | 10 (3) | 7 (4) | 2 (2) | 1 (4) | |
Black | 16 (5) | 7 (4) | 7 (6) | 2 (8) | |
Native American | 1 (0.3) | 1 (1) | 0 (0) | 0 (0) | |
Other | 2 (1) | 0 (0) | 1 (1) | 1 (4) | |
Spanish/Hispanic | 42 (14) | 24 (15) | 14 (11) | 4 (16) | |
White | 237 (77) | 121 (76) | 99 (81) | 17 (68) | |
Type of surgery | NS | ||||
BCT | 203 (66) | 100 (63) | 85 (69) | 18 (72) | |
Mastectomy | 105 (34) | 60 (38) | 38 (31) | 7 (28) | |
Histology | .0225 | ||||
Invasive ductal | 214 (70) | 100 (63) | 91 (74) | 23 (92) | |
Invasive lobular | 37 (12) | 24 (15) | 13 (11) | 0 (0) | |
Other | 57 (19) | 36 (23) | 19 (15) | 2 (8) | |
Pathological stage | NS | ||||
0 | 3 (1) | 3 (2) | 0 (0) | 0 (0) | |
I | 243 (79) | 127 (79) | 97 (79) | 19 (76) | |
IIA | 52 (17) | 25 (16) | 21 (17) | 6 (24) | |
IIB | 7 (2) | 3 (2) | 4 (3) | 0 (0) | |
IIIA | 1 (0.3) | 1 (1) | 0 (0) | 0 (0) | |
IIIB | 1 (0.3) | 1 (1) | 0 (0) | 0 (0) | |
No. of positive lymph nodes | NS | ||||
0 | 286 (93) | 152 (95) | 110 (89) | 24 (96) | |
1 | 15 (5) | 4 (3) | 10 (8) | 1 (4) | |
2 | 2 (1) | 0 (0) | 2 (2) | 0 (0) | |
3 | 1 (0.3) | 1 (1) | 0 (0) | 0 (0) | |
4 | 1 (0.3) | 1 (1) | 0 (0) | 0 (0) | |
Tumor grade | <.0001 | ||||
I | 45 (15) | 31 (19) | 14 (11) | 0 (0) | |
II | 193 (63) | 107 (67) | 80 (65) | 6 (24) | |
III | 70 (23) | 22 (14) | 29 (24) | 19 (76) | |
PR status | <.0001 | ||||
Positive | 272 (88) | 145 (91) | 112 (91) | 15 (60) | |
Negative | 31 (10) | 10 (6) | 11 (89) | 10 (40) | |
Unknown | 5 (2) | 5 (3) | 0 (0) | 0 (0) | |
Ki-67 expression | .0024 | ||||
High (>20%) | 27 (9) | 9 (6) | 11 (9) | 7 (28) | |
Intermediate (10-20%) | 41 (13) | 23 (14) | 16 (13) | 2 (8) | |
Low (<10%) | 48 (16) | 29 (18) | 19 (16) | 0 (0) | |
Not measured | 195 (63) | 99 (62) | 77 (63) | 16 (64) | |
Vascular invasion | .0162 | ||||
Positive | 41 (13) | 16 (10) | 17 (14) | 8 (32) | |
Negative | 267 (87) | 144 (90) | 106 (86) | 17 (68) | |
Tumor size | NS | ||||
<2 cm | 230 (75) | 119 (75) | 93 (76) | 18 (72) | |
≥2 cm | 73 (24) | 38 (24) | 28 (23) | 7 (28) | |
Chemotherapy use | <.0001 | ||||
Yes | 81 (26) | 15 (9) | 47 (38) | 19 (76) | |
No | 227 (74) | 145 (91) | 76 (62) | 6 (24) | |
Hormone therapy use | .0220 | ||||
Yes | 264 (86) | 145 (91) | 100 (81) | 19 (76) | |
No | 44 (15) | 15 (9) | 23 (19) | 6 (24) | |