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Table 2 Echocardiographic data

From: Effects of early and late-onset treatment with carvedilol in an experimental model of aortic regurgitation

 

EARLY

LATE

 

Sham

AR

AR + CAR

Disease p-value

Treatment p-value

AR

AR + CAR

Treatment p-value

 

(n = 8)

(n = 7)

(n = 7)

  

(n = 5)

(n = 7)

 

LVIDd (mm)

9.1 ± 0.24

11.3 ± 0.37

11.1 ± 0.50

0.001*

0,92

10.9 ± 0.50

11.0 ± 0.36

0,92

LVIDs (mm)

5.4 ± 0.23

7.7 ± 0.39

7.6 ± 0.57

0.001*

0,99

6.9 ± 0.46

6.7 ± 0.50

0,88

Wall thickness (mm)

2.0 ± 0.03

2.2 ± 0.07

2.2 ± 0.06

0.019*

0,87

2.4 ± 0.07

2.3 ± 0.08

0,45

FS (%)

41.4 ± 1.50

31.9 ± 1.53

31.70 ± 2.47

0.001*

1,00

37.3 ± 0.02

38.7 ± 0.03

0,75

Strain (%)

−22.15 ± 1.23

−18.5 ± 1.12

−18.5 ± 0.98

0,075

1,00

−17.0 ± 0.38

−18.1 ± 1.16

0,49

  1. Echocardiographic data after twelve (left) and twenty-two (right) weeks of severe AR. Disease p-values indicate difference between sham and untreated (AR) groups. Treatment p-value indicates difference between treated (Carvedilol) and untreated (AR). All p-values are from paired analysis. Left ventricle end-diastolic diameter (LVEDD), left ventricle end-systolic diameter (LVESD), fractional shortening (FS), and wall thickness (WT). *p < 0.05.