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Table 1 Morphometric data at sacrifice

From: Effects of early and late-onset treatment with carvedilol in an experimental model of aortic regurgitation

 

EARLY

LATE

 

Sham

AR

AR + CAR

Disease p-value

Treatment p-value

AR

AR + CAR

Treatment p-value

 

(n = 8)

(n = 7)

(n = 7)

  

(n = 5)

(n = 7)

 

Rat Weight

717 ± 20

666 ± 15

698 ± 17

0,12

0,75

739 ± 54

715 ± 11

0,85

Heart weight (g)

1.66 ± 0.07

2.32 ± 0.12

2.32 ± 0.17

0.003*

1,00

2.27 ± 0.25

2.28 ± 0.15

0,98

LV weight (g)

1.17 ± 0.05

1.69 ± 0.10

1.73 ± 0.13

0.002*

0,95

1.65 ± 0.17

1.72 ± 0.11

0,75

RV weight (g)

0.26 ± 0.01

0.36 ± 0.02

0.32 ± 0.02

0.005*

0,46

0.34 ± 0.05

0.32 ± 0.02

0,70

Lung weight (g)

1.59 ± 0.03

2.00 ± 0.25

2.04 ± 0.35

0,45

0,99

1.72 ± 0.11

1.65 ± 0.05

0,60

  1. Weights at sacrifice in sham, treated (Carvedilol), and untreated (AR) rats. Disease p-values indicate difference between sham and untreated groups. Treatment p–value indicate difference between treated and untreated groups. Left ventricle (LV), right ventricle (RV). *p < 0.05.